Cortactin and Focal Adhesion Kinase as Predictors of Cancer Risk in Patients with Laryngeal Premalignancy Authors:
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TITLE: CORTACTIN AND FOCAL ADHESION KINASE AS PREDICTORS OF CANCER RISK IN PATIENTS WITH LARYNGEAL PREMALIGNANCY AUTHORS: Juan P. Rodrigo, Gustavo Álvarez-Alija‡, Sofía Tirados Menéndez‡, Gonzalo Mancebo, Eva Allonca, Darío García-Carracedo, Manuel Florentino Fresno, Carlos Suárez, Juana María García-Pedrero. 1 Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias and Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain. 2 Servicio de Anatomía Patológica, Hospital Universitario Central de Asturias, Oviedo, Spain. ‡These authors contributed equally to this work. Supported by Fondo de Investigación Sanitaria PI07/0777 (J.P.R.) and CP07/00032 (J.M.G.P.) and FI09/00343 (G.A.A.), FICYT IB09-068 (J.M.G.P.) and BP08-007 (S.T.M.), ISCIII, RTICC (RD06/0020/0034) and Obra Social Cajastur-IUOPA. CORRESPONDENCE: Juana María García-Pedrero, PhD Hospital Universitario Central de Asturias Laboratorio 2 ORL IUOPA 33006 Oviedo, Spain Phone: +34 985107956 E-mail: [email protected] RUNNING TITLE: Cortactin and FAK in laryngeal cancer risk Word count of the text: 2,985
منابع مشابه
Cortactin and focal adhesion kinase as predictors of cancer risk in patients with laryngeal premalignancy.
Novel markers are needed to accurately predict the risk of malignant transformation in laryngeal premalignancies. We therefore investigated the clinical significance of cortactin (CTTN) and focal adhesion kinase (FAK) during laryngeal tumorigenesis and their potential utility as cancer risk markers. CTTN and FAK protein expression and gene amplification were assessed in 82 patients with larynge...
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تاریخ انتشار 2011